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Hope For Fibroids
Poster (PDF)
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NOTE: The new section is not
intended to take the place of seeing a physician for a consultation.
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Case Example: Period stopped after UAE (age 48)
I had the
UAE procedure
performed two years ago (age 48 years). The result was that I
went straight into menopause. My period stopped cold!
Prior to the surgery my "female" hormone levels were normal (not in
the perimenopausal or menopausal range).
Almost immediately after the UAE procedure, I developed high blood
pressure for which I am now taking meds, hot flashes, night sweats,
and I gained some 30 lbs. I have fat everywhere that has
been impossible to lose. Although I am no longer bleeding and
anemic, my post-UAE experience has been and continues to be miserable.
Analysis:
There has been a documented %5+ incidence of menopause post UAE that
is overwhelmingly seen in women 45 y/o or over. The theory is
that since these women are within the normal age of menopause:
· Some coincidentally were fated to go into
menopause at that time – which is not reliably predicted by any but
very specialized hormone analysis or
· The particles used for UAE that normally
enter the arteries supplying the ovaries in this aging ovary are
sufficient to precipitate menopause.
Weight gain, hot flashes and sweats are typical symptoms for many
women in menopause. This is not to make light of what has
happened but this was predictably what was about to happen sooner
rather that later in a woman in this age group whether she had had
'UAE or not.
All these symptoms should be discussed with a gyn. It is
unfortunate when this is not effectively explained to a woman >45
before the procedure.
– Francis Hutchins, M.D.
Medical Article:
Spies JB,
Roth AR, Gonsalves SM, Murphy-Skrzyniarz KM. "Ovarian
Function after Uterine Artery Embolization for Leiomyomata: Assessment
with Use of Serum Follicle Stimulating Hormone Assay", Entrez
PubMed, Interventional Radiology Section, Department of
Radiology of Georgetown University Hospital, 3800 Reservoir Rd. NW, GC
201, Washington, DC 20007-2197, USA.
CONCLUSIONS: Most patients had no change in ovarian function as
measured by basal FSH after UAE. For patients aged 45 or older,
there is approximately a 15% chance of an increase in basal FSH into
the perimenopausal range. |
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Case Example: UAE, Myomectomy, IVF (implant)
I had a myomectomy in 2005, but I still have 6 fibroids left and they
are located in areas that will still prevent me from getting pregnant.
Is
UAE, another
myomectomy, or
IVF (implant) my best option?
Analysis: My first
suggestion would be to make sure that there is no question that you
need to have these fibroids treated to become pregnant. This is
an area of controversy. It is clear that fibroids that are
growing into the cavity of the uterus can be a threat to conception as
well as a developing pregnancy. If you had these you would be
experiencing very heavy periods. Also if the uterus is very
enlarged, for example the size of a 5-month pregnancy, the shear bulk
might make carrying a pregnancy very difficult.
Assuming you need to have some treatment,
UAE is at present an option; especially since you have had a previous
myomectomy. Repeat myomectomies in general are much more
difficult and tend to have more complications. There has been a
debate until recently as to whether UAE is acceptable for women
seeking future pregnancy. My review of the literature and my
experience suggest that it is appropriate - particularly as an
alternative to a repeat myomectomy.
It depends on a number of factors.
Any reluctance arises from their concern that IVF with embryo
implantation is very expensive and the risk of miscarriage is elevated
with fibroids. You should discuss this at length with a
fertility specialist and be willing to get a second opinion. –
Francis Hutchins, M.D. |
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Case Example: Pregnancy and fibroid
I am 19 weeks pregnant, and
the doctor said the placenta is attached to a 12cm fibroid.
Analysis:
If the placenta
attaches over a fibroid the significance depends on the size
of the
fibroid, the amount of the placenta that is attached to it and
whether the fibroid is deep
in the wall or protruding from the wall into the cavity of the uterus.
Depending on the answers to these questions this situation can be
quite serious for the baby. Fortunately, as the pregnancy
progresses the portion of the placenta over the fibroid may move away
due to the growth of the uterus. In this case, one would
expect the problem to go away. - Francis
Hutchins, M.D.
Refer to The Story Behind The Fibroid
Photo, Fibroids
and Pregnancy
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Case Example: Fibroids, Pregnancy, Abortion I am 3 months
pregnant, still in pain, and considering terminating the pregnancy.
I have multiple fibroids that are as follows: right side measures over
7cm, left side around 7, and one on top of my uterus. The right
fibroid is partly blocking my cervix. I was informed that this
might cause complications during the abortion. I am getting
conflicting viewpoints from my doctors. I am concerned about
keeping my fertility.
Analysis:
Your first decision involves choosing a competent physician. Then
leave the mechanics such as where the procedure should be done to that
physician. That is the kind of technical input that you are paying
for. Yes, fibroids can complicate the performance of an abortion.
The decision is yours and all the opinions in the world will not
change that.
There is risk with everything in life and certainly with medical
treatment. In spite of this, the overwhelming majority of
women who undergo a termination at this stage of pregnancy undergo it
safely and their fertility is not affected.
- Francis Hutchins, M.D.
Refer to Pregnancy and
Fibroids:
Pregnancy and Contraception.
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Case Example: Pregnancy, Pain, Medications
I am currently 13 weeks pregnant, in a lot of pain and unsure of what
to do with regard to my pregnancy. I have uterine fibroids,
which caused me pain before my pregnancy. I was told it
would be difficult for me to get pregnant due to my age (35) and the
fibroids. So the pregnancy was definitely a surprise. The
pain has been excruciating at times and I have not been able to work
because I am so uncomfortable. I am currently taking ibuprofen
for pain. In the severe episodes I have taken Darvocet and was
even given a shot of Demerol. I am very concerned about the
effect of the medication on the baby and about moving forward with the
pregnancy knowing I may be in this much pain and this uncomfortable.
I am also scared if I don't try to carry the baby because my OB/Gyn
has made me feel like this may be my only chance to have a baby.
I don't know if that is true. I really need some more
information regarding my options for pain relief, the possible effects
on my pregnancy, and my fertility in general. I also am scared
about the effects of termination on my health and future fertility.
Analysis:
The most important fact for you
to remember is that pain from fibroid degeneration at this stage is
not unusual and you are taking the standard drugs, ibuprofen and
Demerol, used to treat this. They have been used without harm to
pregnancy.
The good news is
that this pain tends to get better and often resolves at or about 24
weeks of gestation.
Pregnancy
termination is considered one of the safest procedures in medicine but
that is not to say that complication won’t occur to somebody sometime.
Your fertility at this point appears to be intact since you are
pregnant. If this pregnancy is not carried you will still be
faced with the need for removal of the tumors and that could interfere
with fertility because of scarring.
I think you need to seek support through a close relationship with a
caring OB/Gyn or other support person. Most of these pregnancies
turn out well but occasionally termination is chosen.
- Francis Hutchins, M.D. |
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Case Example: Fibroid Growth After A Myomectomy
I had an
abdominal myomectomy
June 2005, at which time nine (9) fibroids were removed.
Now, in Dec. 2005, I have new fibroids. I am wondering how
unusual this is? My surgeon said he removed all the fibroids he
could see and feel. Is it possible the doctor missed some?
Should I be concerned about my hormones, particularly estrogen, if
fibroids are growing this fast after a myomectomy? I realize I
need to visit my doctor, but I am trying to understand why my fibroids
and bulk symptoms would return so soon after myomectomy.
Analysis:
I wonder
how you know that your fibroids have recurred. Ultrasound, MRI,
examination or possibly you are basing this on symptoms.
If it is symptoms that can be very unreliable since many things can
cause similar symptoms.
A
fibroid uterus usually contains many fibroids some because of size are
very obvious. Others are very small and difficult to see.
In addition, to remove all fibroids can be quite challenging because
it may require such extensive dissection as to result for all
practical purposes in destruction of the uterus.
Therefore, the goal of myomectomy is to;
1.
remove all symptomatic tumors
2. remove all obvious tumors that could predictably lead to further
problems in the near future.
It is
always the goal to remove all tumors if feasible. Even if all tumors
are removed it is recognized that there is the possibility of
recurrence because
1.
some tumors are too small to be seen
2. the uterus will always retain the genetic basis for forming
fibroids again.
I agree,
it is surprising that you would have a recurrence so soon but first it
must be confirmed.
- Francis Hutchins, M.D. |
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Case Example: Bleeding, Endometrial Ablation, and
Alternatives
I am in my late 40’s and I have had heavy bleeding for approximately
two years. It started out lasting a week and now it lasts
for three weeks out of the month. I was given all the tests and
a couple of small fibroids were discovered. I tried an
Endometrial Ablation, but
the fluid going in wasn't coming out so my doctor stopped the
procedure. Other doctors have said that ablation won't work with
fibroids but I don't know if it will or not. I am now on a low
dose of birth control pills and for 3-4 months the pills seemed to be
working. Recently I have been experiencing bleeding
problems again even with being on the pill. I am trying to find
a way to get to menopause naturally. I would like to avoid a
hysterectomy if possible, but I am feeling like I don't have other
treatment options available for my situation.
Analysis:
You would appear to potentially
have several options all of which would not include hysterectomy:
- Adjust
birth control pill dosage.
- Endometrial Ablation
coupled – the fact that there was difficulty with fluid control only
applies to that one attempt and the operator.
Fluid control
is usually manageable.
- Global Ablation – new
group of techniques many of which can treat fibroids in the cavity
which you likely have.
-
MRI Focused
ultrasound – new, not universally available and expensive.
-
Uterine Artery
Embolization – very effective for bleeding with fibroids.
- Hormonal therapy with
potent progestin.
- Lupron (GnRH analogue) – can be
given intermittently for 3-6 months at a time.
As you can see
there are potentially many alternatives. Much of this is
dependant on the Gyn you are working with.
-
Francis Hutchins, M.D.
Analysis:
Many women with fibroids can have a successful endometrial ablation,
especially if they are close to menopause. In this case, the
fluid problem makes me think that the gynecologist did not have the
experience to do such a procedure.
Ablation,
especially in the presence of fibroids, requires a great deal of
experience and skill in
hysteroscopic surgery. This is not something that most
gynecologists will have. Years ago I published a series of
hysteroscopic treatment of abnormal bleeding in women with fibroids
with excellent overall results. (1) In order to make the proper
decision on how to treat heavy bleeding you should see a gynecologist
who is knowledgeable about all surgical and non-surgical options.
- Paul Indman, M.D.
Medical Article:
Indman PD.
Hysteroscopic
treatment of menorrhagia associated with uterine leiomyomas.
(Entrez
Pubmed)
Obstet
Gynecol. 1993 May;81(5 ( Pt 1)):716-20.
OBJECTIVE: To determine the effectiveness of
hysteroscopic treatment of menorrhagia associated with uterine
leiomyomas. CONCLUSION: Hysteroscopic treatment of menorrhagia
associated with uterine myomas can be effective in carefully selected
patients. |
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Case Example:
Asymptomatic Uterine Fibroids and Fertility
I discovered last year that I have three
fibroids - two small intramural and one large serous (9cm).
Apart from some pressure symptoms about a week before a period
(bladder pressure and some back pain) I am virtually
asymptomatic. My GP suggested I
leave them alone whereas my Gyn wants me to be more proactive.
Part of
me is reluctant to go through any procedure which would cause any pain
or discomfort and which may reduce whatever fertility I have left (I'm
39). At the same time I don't want to wait until it gets so
large that it is putting even more pressure on my organs and I would
be of an age where there was an increased risk of premature menopause.
If I opt for any treatment I would prefer embolization.
Analysis:
The
primary indication for treatment of fibroids is to improve symptoms.
It does not appear that your symptoms are an issue for you.
It might not
continue to grow. Even if it does grow it may do so at a very
slow rate. If it does grow it may not be any more symptomatic.
If it does become symptomatic you still would likely be a candidate
for conservative therapy such as UAE.
I am
being the devil’s advocate in order to give you a perspective.
These thing are not very predictable and the downside risk is not
necessarily that great.
You are
correct regarding fertility. There is a risk that should you
have surgery or any other intervention your fertility may be decreased
assuming that your fertility is intact now.
I hope I
have added to your understanding but I also realize that more
information may cause you more confusion. Nevertheless knowledge
is always good. If you are undecided, sit back and cogitate for
a while and continue your search for the truth.
-
Francis Hutchins, M.D. |
Pregnancy - Fertility
continued Page:
#3b
******
Legal Note: The material presented on Hope For Fibroids Inc.
web site is for informational purposes only. It is not meant to
be a substitute for physician care.
If you need medical advice on uterine fibroid
disease or other medical conditions you should discuss them with a
physician.
Last modified:
Monday January 01, 2007 |
Copyright 2005-2007
Hope For Fibroids Inc.
(web
site designed & developed by
Hope)
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Francis Hutchins, Jr., M.D.

Paul Indman, M.D.
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CASE
EXAMPLES (#3)
Fertility/Pregnancy
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Period stopped
after UAE |
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UAE,
Myomectomy, IVF (implant) |
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Placenta attached to fibroid |
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Fibroids, Pregnancy, Abortion |
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Pregnancy, Pain, Medications |
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Fibroid growth after Myomectomy |
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Bleeding, Endometrial Ablation, Alternatives |
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Asymptomatic Uterine Fibroids and Fertility |
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Case: #1
Case:
#2
Case: #3b
Case:
#4 Menopause
Case:
#5
Case Listing
Pedunculated
Fibroid Photo |
Medical Terms |
| Notes
On Insurance |
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