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MR guided Focused Ultrasound

Patient selection guidelines in MR-guided focused ultrasound surgery of uterine fibroids: a pictorial guide to relevant findings in screening pelvic MRI.  Yoon SW, Lee C, Cha SH, Yu JS, Na YJ, Kim KA, Jung SG, Kim SJ.

Eur Radiol. 2008 Jul 11. [Epub ahead of print]
(PDF 547 KB) - Permission by Dr. Sang-Wook Yoon)

Department of Diagnostic Radiology, College of Medicine, Pochon CHA University Bundang CHA General Hospital, 351, Yatap-dong, Bundang-gu, Sungnam-si, Gyunggi-do, Republic of Korea, 463-712, jansons@cha.ac.kr.   PubMed

"Uterine leiomyomas (fibroids), the most common benign tumor in women of childbearing age, can cause symptoms including dysmenorrhea, menorrhagia, urinary symptoms, pain and infertility. Hysterectomy is a common approach to treating uterine fibroids, and less invasive surgical approaches such as myomectomy and uterine artery embolization also have been shown to alleviate symptoms.

Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is the only totally non-invasive surgical approved method for treating uterine fibroids. In clinical trials, MRgFUS resulted in significant relief of uterine fibroid symptoms. The safe and effective use of MRgFUS is affected by fibroid type and location, position relative to adjacent anatomical structures and the presence of co-existent pelvic disease. Additionally, successful outcomes with MRgFUS have been correlated with the volume of fibroids ablated during the procedure. Thus, selection of patients in whom sufficient fibroid volumes can be treated safely using the MRgFUS system is critical for successful outcomes.

The MR images in this pictorial essay provide examples of uterine fibroids for which MRgFUS should be considered and is designed to facilitate the selection of patients for whom MRgFUS is most likely to provide sustained symptom relief." 


Cost-effectiveness of magnetic resonance-guided focused ultrasound surgery for treatment of uterine fibroids. 
Zowall H, Cairns JA, Brewer C, Lamping DL, Gedroyc WM, Regan L.  BJOG. 2008 Apr;115(5):653-62. PubMedCentral

"OBJECTIVE: To estimate the cost-effectiveness of a treatment strategy for symptomatic uterine fibroids, which starts with Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) as compared with current practice comprising uterine artery embolisation, myomectomy and hysterectomy." 
 

Non-invasive magnetic resonance imaging-guided focused ultrasound treatment for uterine fibroids - early experience. Morita Y, Ito N, Hikida H, Takeuchi S, Nakamura K, Ohashi H PubMed     

"CONCLUSION: MRgFUS can safely be used to non-invasively treat symptomatic uterine fibroids and avoid the need for surgical intervention in the short term. With large treatment volumes, MRgFUS also results in significant fibroid shrinkage in a relatively short time. Additional follow-up is needed to determine the long-term durability of this promising non-invasive approach."
 



Legal Note:
  The material presented on Hope For Fibroids, Inc. web site is for informational purposes only.  It is not meant to be a substitute for physician care. 
If you need medical advice on uterine fibroid disease or other medical conditions you should discuss them with a physician.

Last modified:  Tuesday July 29, 2008
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